| 11 Florida at Kentucky | 6 or 7pm | ESPN or SECN | |
| Mississippi State at 7 Texas A&M | 6 or 7pm | ESPN or SECN | |
| Tennessee at Missouri | 12:00pm | SECN | |
| Memphis at Temple | 12:00pm | ESPNU | |
| Texas at TCU | 12:00pm | ABC | |
| Duke at 21 North Carolina | 12:00pm | ESPN2 | |
| Western Michigan at Buffalo | 12:00pm | CBSSN | |
| 16 Arkansas at 2 Georgia | 12:00pm | ESPN | |
| Toledo at UMass | 12:00pm | FloFootball / NESN or NESN+ | |
| Minnesota at Purdue | 12:00pm | BTN | |
| 19 Michigan at 18 Wisconsin | 12:00pm | FOX | |
| Charlotte at Illinois | 12:00pm | BTN | |
| Pitt at Georgia Tech | 12:00pm | ACCN | |
| Louisville at Wake Forest | 12:30pm | RSN/ESPN3 | |
| Appalachian State at Georgia State | 2:00pm | ESPN+ | |
| USC at Colorado | 2:00pm | P12N | |
| 8 Cincinnati at 12 Notre Dame | 2:30pm | NBC | |
| Eastern Michigan at NIU | 2:30pm | ESPN+ | |
| ULM at 17 Coastal Carolina | 2:30pm | ESPN+ | |
| Ohio at Akron | 3:30pm | ESPN3 | |
| Central Michigan at Miami (Ohio) | 3:30pm | ESPN+ | |
| UCF at Navy | 3:30pm | CBSSN | |
| 4 Oregon at Stanford | 3:30pm | ABC | |
| Nevada at Boise State | 3:30pm | FS1 | |
| Tulane at East Carolina | 3:30pm | ESPN+ | |
| Bowling Green at Kent State | 3:30pm | ESPN+ | |
| Texas Tech at West Virginia | 3:30pm | ESPN2 | |
| Troy at South Carolina | 3:30pm | SECN | |
| 4 Oklahoma at 25 Kansas State | 3:30pm | FOX | |
| 10 Ohio State at Rutgers | 3:30pm | BTN | |
| Syracuse at Florida State | 3:30pm | ACCN | |
| FIU at Florida Atlantic | 3:30pm | Stadium | |
| 13 Ole Miss at 1 Alabama | 3:30pm | CBS | |
| USF at SMU | 4:00pm | ESPNU | |
| Arkansas State at Georgia Southern | 4:00pm | ESPN+ | |
| Army at Ball State | 5:00pm | ESPN+ | |
| Washington State at California | 5:30pm | P12N | |
| UNLV at UTSA | 6:00pm | ESPN+ | |
| Louisiana Tech at NC State | 6:00pm | ACCNExtra/ESPN+ | |
| Southern Miss at Rice | 6:30pm | ESPN3 | |
| Air Force at New Mexico | 6:30pm | FS2 | |
| Liberty at UAB | 7:00pm | CBSSN | |
| Marshall at Middle Tennessee | 7:00pm | Stadium | |
| Baylor at Oklahoma State | 7:00pm | ESPN2 | |
| Kansas at 14 Iowa State | 7:00pm | FS1 | |
| Indiana at 6 Penn State | 7:30pm | ABC | |
| Boston College at 9 Clemson | 7:30pm | ACCN | |
| WKU at 20 Michigan State | 7:30pm | BTN | |
| Northwestern at Nebraska | 7:30pm | BTN | |
| UConn at Vanderbilt | 7:30pm | ESPNU | |
| Louisiana at South Alabama | 8:00pm | ESPN+ | |
| 23 Auburn at LSU | 9:00pm | ESPN | |
| Old Dominion at UTEP | 9:00pm | ESPN+ | |
| Washington at Oregon State | 9:00pm | P12N | |
| Arizona State at 24 UCLA | 10:30pm | FS1 | |
| New Mexico State at San Jose State | 10:30pm | NBCSCA | |
| 22 Fresno State at Hawaii | 11:00pm | CBSSN | |
